Elephantiasis of the leg, from a 27-year-old man from Buffalo, NY. Elephantiasis is usually characterized by lymphatic derangement caused by filarial worms or parasitic roundworms that are endemic to the tropics. The patient had never been to any region where these parasites were, so doctors didn’t know the origin of his elephantiasis.
Leg amputated in 1897. Patient made full and uneventful recovery after amputation, with continued lymphatic symptoms causing only mild edema in right leg.