Brain displaying necrosis due to carbon monoxide poisoning
In the past, carbon monoxide toxicity was not unheard of, especially during the winter. Cold nights and CO-producing fires lead to a silent death while asleep.
Though people were aware that they needed ventilation when fires were burning, frigid cold outside leading to people keeping too much air out, and having a stove burning through the night (so as not to freeze to death…), led to at least several dozen documented deaths throughout the Midwestern United States in the 1890s.
A Text-Book of Pathology. W. G. MacCallum, 1916.
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